Figure 3.

Local sequence contexts of acetylation and succinylation sites. (A) A consensus sequence logo of −10 to +10 positions relative to the acetylation (left) and succinylation (right) sites were generated using the iceLogo algorithm. The frequencies are shown as percentage differences (P = 0.05). (B) Sequence motifs surrounding the acetylation (left) and succinylation (right) sites were analyzed using the Motif‐X algorithm. The parameters were as follows: width, 13 residues (six amino acids on each side of a modification site); occurrence threshold, 20; P‐value threshold, 0.000001 for acetylation and 0.001 for succinylation; and background, unaligned motif data.