Table 2. Enriched canonical pathways in ACSL4-overexpressing MCF-7 cells.

Ingenuity Canonical Pathways	−log(p-value)
EIF2 Signaling	21.2
Protein Ubiquitination Pathway	14.6
Regulation of eIF4 and p70S6K Signaling	8.88
Molecular Mechanisms of Cancer	8.26
mTOR Signaling	8.18
Mitochondrial Dysfunction	7.47
NRF2-mediated Oxidative Stress Response	6.88
Cell Cycle: G1/S Checkpoint Regulation	6.81
ATM Signaling	6.81
Hypoxia Signaling in the Cardiovascular System	6.67
Oxidative Phosphorylation	6.25
PI3K/AKT Signaling	6.19
14–3-3-mediated Signaling	5.72
NGF Signaling	5.50
PTEN Signaling	5.14
Antiproliferative Role of TOB in T Cell Signaling	5.12
Pancreatic Adenocarcinoma Signaling	4.94
D-myo-inositol (1,3,4)-trisphosphate Biosynthesis	4.76
ERK5 Signaling	4.66
Type II Diabetes Mellitus Signaling	4.66
Hereditary Breast Cancer Signaling	4.55
TGF-β Signaling	4.55

IPA analysis of RNA-Seq data towards canonical pathways. Pathways are shown which were designated significantly enriched by the software, with a p-value < 0.05 by Fisher's Exact test.