Skip to main content
. 2015 Oct 13;6(40):42667–42686. doi: 10.18632/oncotarget.5626

Figure 5. Akt1 regulates NF-kB activity in NSCLC cells.

Figure 5

A. Immunoblot analysis of members of the NF-kB pathway in PEd/10 and derivative cells treated with increasing doses of TNF-α (0.1, 1 ng/ml). B. Immunoblot analysis of members of the NF-kB pathway in BEAS-C and BEAS-Akt1-E17K cells. C. Luciferase assay of NF-kB activity in NCI-H460, PEd/10 cells and derivatives interfered for Akt1 transfected with a reporter containing a NF-kB-responsive promoter, *p < 0.05. D. Immunoblot analysis of IkBα in NCI-H460 and PEd/10 cells treated with BAY11-7082. E. Analysis of spheroid forming capability of NCI-H460 and PEd/10 cells treated with BAY11-7082, *p < 0.05, ***p < 0.001.