Skip to main content
. 2015 Oct 17;6(40):42773–42780. doi: 10.18632/oncotarget.6001

Table 2. Association between biomarkers of DNA damage and repair (γ-H2AX and pChk1) and pathological complete response in TNBC patients treated with neoadjuvant chemotherapy (N = 66).

Biomarker Pathological complete response Chi2
No Yes
N (%) N (%) p-value
γ-H2AXlow 18 (56.2) 14 (43.8) 0.009
γ-H2AXhigh 29 (85.3) 5 (14.7)
pChk1neg 10 (55.6) 8 (44.4) 0.085
pChk1pos 37 (77.1) 11 (22.9)