Table 2. Association between biomarkers of DNA damage and repair (γ-H2AX and pChk1) and pathological complete response in TNBC patients treated with neoadjuvant chemotherapy (N = 66).
Biomarker | Pathological complete response | Chi2 | |
---|---|---|---|
No | Yes | ||
N (%) | N (%) | p-value | |
γ-H2AXlow | 18 (56.2) | 14 (43.8) | 0.009 |
γ-H2AXhigh | 29 (85.3) | 5 (14.7) | |
pChk1neg | 10 (55.6) | 8 (44.4) | 0.085 |
pChk1pos | 37 (77.1) | 11 (22.9) |