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. 2015 Oct 19;6(40):42854–42867. doi: 10.18632/oncotarget.5733

Table 1. Correlation of clinicopathological features of breast cancer with HRD1 expression levels.

Characteristics All cases HRD1 expression levels
High expression Low expression P value
Age 0.552
 <50 86 32 54
 ≥50 84 35 49
Tumor size (cm) 0.225
 <2 74 33 41
 ≥2 96 34 62
Grade 0.023*
 I, well-differentiated 23 14 9
 II, moderately differentiated 99 40 59
 III, poorly differentiated 48 13 35
Tumor histological 0.064
 Ductal carcinoma in situ 23 14 9
 Invasive ductal carcinoma 130 48 82
 Invasive lobular carcinoma 17 5 12
ER status 0.989
 Negative 61 24 37
 Positive 109 43 66
PR status 0.557
 Negative 79 33 46
 Positive 91 34 57
HER2/neu status 0.776
 Negative 112 45 67
 Positive 58 22 36
IGF-1R status 0.000*
 Negative 57 36 21
 Positive 113 31 82
Lymph node-metastasis 0.000*
 Negative 90 57 33
 Positive 80 10 70
Nuclear p65 expression
 High expression 60 37 23 0.000*
 Low expression 110 30 80