Table 1. Patient characteristics at time of metastases diagnosis (n = 379).
Characteristics | No. | % |
---|---|---|
Median age (years, range) | 49 (25–76) | |
<40 | 73 | 19.3 |
≥40 | 306 | 80.7 |
Pathological types | ||
Invasive ductal carcinoma | 355 | 93.7 |
Others | 24 | 6.3 |
Menstruation status | ||
Pre- or peri-menopausal | 179 | 47.2 |
Post-menopausal | 200 | 52.8 |
ECOG performance status | ||
0 | 87 | 23.0 |
1 | 281 | 74.1 |
≥2 | 11 | 2.9 |
Time between breast surgery and recurrent disease(months, range) | 14.3 (0–217.0) | |
<12 | 133 | 35.1 |
≥12 | 224 | 59.1 |
de novo metastatic | 22 | 5.8 |
Number of metastatic organ sites | ||
1 | 126 | 33.2 |
2 | 143 | 37.7 |
≥ 3 | 110 | 29.0 |
Metastatic sites | ||
Lymph node | 230 | 60.7 |
Lung | 163 | 43.0 |
Chest wall | 108 | 28.5 |
Bone | 99 | 26.1 |
Liver | 76 | 20.1 |
Pleura | 32 | 8.4 |
Brain | 11 | 2.9 |
Breast | 4 | 1.1 |
Type of metastasis | ||
Visceral | 212 | 55.9 |
Non-visceral | 167 | 44.1 |
Adjuvant or neo-adjuvant chemotherapy | ||
Yes | 341 | 90.0 |
Anthracyclines only | 106 | 28.0 |
Taxanes only | 24 | 6.3 |
Both Anthracyclines and Taxanes | 192 | 50.7 |
With Platinum | 36 | 9.5 |
Without Platinum | 305 | 80.5 |
No | 38 | 10.0 |
Abbreviations: ECOG, Eastern Cooperative Oncology Group