Table 2.

Age group-adjusted odds ratios per age-adjusted standard deviation, with corresponding 95% confidence intervals, and the Hosmer–Lemeshow goodness-of-fit chi-square for log-transformed risk scores

Log-transformed risk score	OR*	(95% CI)	P	χ2†	P
SNP-based	1.46	(1.29, 1.64)	2.4 × 10−16	11.4	0.2
BOADICEA	1.8	(1.57, 2.07)	2.6 × 10−12	20	0.01
BOADICEA and SNP-based	1.96	(1.71, 2.24)	8.3 × 10−11	9.9	0.3
BRCAPRO	1.75	(1.52, 2.02)	5.7 × 10−7	14.4	0.1
BRCAPRO and SNP-based	1.89	(1.66, 2.16)	5.6 × 10−10	8.9	0.4
BCRAT	1.67	(1.43, 1.95)	4.1 × 10−23	7.7	0.5
BCRAT and SNP-based	1.8	(1.55, 2.10)	5.5 × 10−21	7	0.5
IBIS	1.3	(1.16, 1.45)	3.0 × 10−14	7.9	0.4
IBIS and SNP-based	1.52	(1.35, 1.71)	2.6 × 10−12	7.2	0.5

^*adjusted for age group;

^†Hosmer–Lemeshow goodness-of-fit test using 10 groups (8 degrees of freedom) Abbreviations: OR, odds ratio; CI, confidence interval