Table 3.

Least-squares mean relative telomere length z-scores (standard errors) by latent classes of phobic symptom scores in 2004 (N=3,194)^a,b

	CCI score in 2004
	Severe	Minimal/ intermediate	Non-anxious	F; Pvaluef
N	80	2436	678
Median CCI in 1988 (range)	2 (0-3)	2 (0-3)	1 (0-3)
Median CCI in 2004 (range)	8 (7-13)	2 (1-6)	0 (0-0)
Model Ic	−0.15 (0.11)	0.03 (0.02)	−0.02 (0.04)	1.88; 0.15*
Model IId	−0.12(0.11)	0.03 (0.02)	−0.03 (0.04)	1.80; 0.17**
Model IIIe	−0.12 (0.11)	0.03 (0.02)	−0.03 (0.04)	1.77; 0.17***

Abbreviations: CCI=Crown-Crisp Index. Degrees of freedom=df.

^aGeneralized linear model analysis conducted across three mutually exclusive classes of CCI scores in 2004: 1) women with severe CCI in 2004 (N=80), 2) women with minimal/intermediate CCI in 2004 (N=2,436), and 3) women who were non-anxious in 2004 (N=678).

^bAll women had no meaningful anxiety symptoms at baseline (CCI=0-3).

^cAdjusted for age (continuous, in years).

^dAdjusted for model I covariates plus CCI in 1988 (continuous), body mass index (BMI) (continuous, in kg/m²), physical activity (continuous, MET-hours/week), pack years of smoking (continuous), paternal age at participant’s birth (15 to <25 years, 25 to <30 years, 30 to <35 years, 35 to <40 years, ≥40 years, missing), antidepressant use (no, yes, missing), race (non-Hispanic white, other), and education (RN, bachelor, graduate degree).

^eAdjusted for model II variables plus hypertension (yes, no), dyslipidemia (yes, no), diabetes (yes, no), cardiovascular disease (yes, no), respiratory disease (yes, no) and cancer (yes, no).

^fF-test statistic and P_value are from the global test for differences in least-squares means.

^*F_{numerator df, denominator df} = F_{2, 3190}

^**F_{numerator df, denominator df} = F_{2, 3174}

^***F_{numerator df, denominator df} = F_{2, 3168}