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. Author manuscript; available in PMC: 2016 Jun 14.
Published in final edited form as: Lab Invest. 2015 Dec 14;96(3):270–282. doi: 10.1038/labinvest.2015.147

Figure 5.

Figure 5

VE-cadherin blockade induced increased lymphatic vessel loops within newly synthesized corneal lymphatic vessels in vivo. Suture induced corneal inflammation was used to stimulate new lymphatic vessel growth in 129/SV mice. Mice treated with neutralizing antibodies to VE-cadherin developed significantly more lymphatic vessel loop structures compared to isotype control treated mice (A-C). The lymphatic vessel density and sprout formation was similar between these groups (D and E). The data shown is from 3 independent experiments with 4 mice in each group, each dot representing a cornea. The bracket indicates a statistically significant difference. The size standards are 100 μm.