Table 1.
Characteristics of cases and controls in the AMBER Consortium, by study.
| Characteristics | BWHS | CBCS | MEC | WCHS | Total | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Cases N (%) | Controls N (%) | Cases N (%) | Controls N (%) | Cases N (%) | Controls N (%) | Cases N (%) | Controls N (%) | Cases N (%) | Controls N (%) | |
| Age, yearsa,b | ||||||||||
| <45 | 327 (19) | 2,549 (24) | 236 (29) | 216 (27) | 0 (0) | 0 (0) | 267 (25) | 307 (25) | 830 (18) | 3,072 (18) |
| 45–55 | 572 (33) | 3,521 (33) | 247 (31) | 275 (35) | 59 (6) | 341 (7) | 334 (31) | 439 (36) | 1,212 (26) | 4,576 (26) |
| 55–64 | 529 (30) | 3,005 (28) | 175 (22) | 159 (20) | 222 (23) | 1,131 (24) | 335 (31) | 375 (31) | 1,261 (28) | 4,670 (27) |
| ≥65 | 312 (18) | 1,710 (16) | 148 (18) | 138 (18) | 674 (71) | 3,188 (68) | 149 (14) | 100 (8) | 1,283 (28) | 5,136 (29) |
| First degree family history of breast cancerb | 270 (15) | 1,008 (9) | 132 (16) | 88 (11) | 140 (15) | 385 (8) | 184 (17) | 141 (12) | 726 (16) | 1,622 (9) |
| First degree family history of cancers other than breast cancer | ||||||||||
| Prostate cancera,b | 180 (10) | 799 (7) | 45 (6) | 59 (8) | 93 (10) | 365 (8) | 143 (13) | 107 (9) | 461 (10) | 1,330 (8) |
| Lung cancerb | 154 (9) | 857 (8) | 66 (8) | 59 (8) | 90 (9) | 340 (7) | 109 (10) | 93 (8) | 419 (9) | 1,349 (8) |
| Colorectal cancera,b | 119 (7) | 608 (6) | 48 (6) | 45 (6) | 76 (8) | 363 (8) | 71 (7) | 69 (6) | 314 (7) | 1,085 (6) |
| Ovarian cancera,b | 62 (4) | 331 (3) | 18 (2) | 16 (2) | 26 (3) | 182 (4) | 22 (2) | 31 (3) | 128 (3) | 559 (3) |
| Lymphoma or leukemiaa,b | 22 (1) | 88 (1) | 32 (4) | 17 (2) | 22 (2) | 87 (2) | 28 (3) | 33 (3) | 103 (2) | 224 (1) |
| Cervical cancera,b | 6 (0) | 25 (0) | 20 (3) | 18 (2) | 10 (1) | 28 (1) | 19 (2) | 19 (2) | 55 (1) | 90 (1) |
a
Chi-square test for difference between studies among cases, p<0.05
b
Chi-square test for difference between studies among controls, p<0.05