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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2016 Jan 14;36(3):510–517. doi: 10.1161/ATVBAHA.115.307034

Figure 1. Role of FXII and FXI in clotting times.

Figure 1

Recalcified whole blood (A, D), pooled human plasma (PPP; B, E) or coagulation-factor depleted plasma (C, F) was incubated with indicated FXI function blocking antibody, FXII inhibitor (CTI) or direct thrombin inhibitor (hirudin). aPTT (A–C) or PT (D–F) was recorded as described in Methods. *indicates significantly different, p < 0.05, clotting time vs. vehicle (mean±SEM).