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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2016 Jan 14;36(3):510–517. doi: 10.1161/ATVBAHA.115.307034

Figure 4. Presence of collagen and TF promotes distal platelet consumption.

Figure 4

Recalcified whole blood was perfused through a 200 mm chamber (coated with either BSA, collagen or collagen + 0.01 – 1.0 nM TF) and allowed to react in flow for 30 sec (residence time) before being collected into a reaction quenching solution at 1 min intervals. Quantification of platelet activation, microaggregate formation and single platelet consumption using FACS (A) for at least five experiments are reported (mean±SEM). In parallel experiments, whole blood was pretreated with a GPIIb-IIIa inhibitor, Eptifibatide (B).