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. Author manuscript; available in PMC: 2016 Mar 9.
Published in final edited form as: Cell Rep. 2016 Feb 11;14(7):1581–1589. doi: 10.1016/j.celrep.2016.01.055

Figure 1. cebp-2 is required for infection response gene induction upon P. aeruginosa PA14 infection.

Figure 1

(A-C) irg-1p::GFP animals treated with either (A) L4440 RNAi control, (B) zip-2 RNAi, or (C) cebp-2 RNAi and infected with PA14. (D-F) irg-1p::GFP expression in (D) wild-type, (E) zip-2(tm4248), or (F) cebp-2(tm5421) animals infected with PA14. In (A)-(F), green is irg-1p::GFP, red is myo-2::mCherry expression in the pharynx as a marker for presence of the transgene. Images are overlays of green, red and Nomarski channels and were taken with the same camera exposure for all. Scale bar, 200 μm. (G) qRT-PCR comparison of PA14-induced gene expression in control RNAi (L4440), zip-2 RNAi, and cebp-2 RNAi treated animals. (H) qRT-PCR comparison of PA14-induced gene expression in wild-type, zip-2(tm4248), and cebp-2(tm5421) animals. For (G) and (H), results shown are the average of two independent biological replicates, error bars are SD. ** p < 0.01, * p < 0.05 with a two-tailed t test.