Table 5. Association between feeling rested when wake up and prostate cancer in the Health Professionals Follow-up Study, 2004-2010.

	Most of the time	Sometimes	Never
All Prostate Cancer, No.	685	185	60
Age-Adjusted RR(95% CI)	Ref.	0.85(0.72-1.01)	1.08(0.83-1.42)
Multivariable-Adjusted RR(95% CI)	Ref.	0.88(0.74-1.04)	1.12(0.85-1.47)
Lethal Prostate Cancer, No.	33	11	6
Age-Adjusted RR(95% CI)	Ref.	1.04(0.52-2.07)	2.49(1.01-6.10)
Multivariable-Adjusted RR(95% CI)	Ref.	1.27(0.61-2.63)	3.05(1.15-8.10)
Advanced Prostate Cancer, No.	49	15	7
Age-Adjusted RR(95% CI)	Ref.	0.92(0.51-1.66)	1.81(0.81-4.09)
Multivariable-Adjusted RR(95% CI)	Ref.	0.99(0.54-1.83)	2.08(0.88-4.88)
Grade 8-10 Prostate Cancer, No.	95	22	10
Age-Adjusted RR(95% CI)	Ref.	0.75(0.47-1.19)	1.58(0.81-3.06)
Multivariable-Adjusted RR(95% CI)	Ref.	0.74(0.46-1.19)	1.66(0.84-3.29)

Multivariable: Adjusted for age, sleep duration, race, vigorous activity level, smoking, diabetes, family history of prostate cancer, snoring status, beta blocker use, PSA testing, marital status, coffee intake, multivitamin use, energy intake, alcohol intake, and number of urinations per night.

^*Lethal: N1/M1, bone or organ mets over follow-up or death from prostate cancer; Advanced: T3b/T4/N1/M1 + N1 or M1 or mets to other organs over follow-up or death from prostate cancer