Figure 3. Elongation dynamics correlate domain architecture.

(A) Cumulative distributions of normalized ribosome densities within and outside of protein-folding domains. Mean normalized RPF densities (z_ij, Eqn S7) for codons within the domain-encoding and non-domain-encoding regions were individually calculated for each ORF. Domain assignments were based on InterProScan classifications (Jones et al., 2014) obtained from the Superfamily database (Wilson et al., 2009). Statistical significance was evaluated using paired t-test (p < 10⁻²⁶).

See also Figure S4.