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. 2016 Feb 9;16(1):109–127. doi: 10.1007/s40268-016-0122-3

Table 5.

p values for differences in slope estimates between formulations by storage temperature

Treatment combination comparison Adjusted p value
B5 2–8 °C vs. B7 2–8 °C 1.000
B5 2–8 °C vs. B9 2–8 °C 1.000
B5 2–8 °C vs. B 2–8 °C 1.000
B7 2–8 °C vs. B9 2–8 °C 1.000
B7 2–8 °C vs. B 2–8 °C 1.000
B9 2–8 °C vs. B 2–8 °C 1.000
B 2–8 °C vs. A 2–8 °C 1.000
B 2–8 °C vs. C 2–8 °C 1.000
C 2–8 °C vs. A 2–8 °C 1.000
B5 RT vs. B7 RT 1.000
B5 RT vs. B9 RT 1.000
B5 RT vs. B RT 1.000a
B7 RT vs. B9 RT 1.000
B7 RT vs. B RT 0.578a
B9 RT vs. B RT 1.000a
B RT vs. A RT 0.747
B RT vs. C RT 1.000
C RT vs. A RT 1.000
B5 40 °C vs. B7 40 °C 1.000
B5 40 °C vs. B9 40 °C 1.000
B5 40 °C vs. B 40 °C 0.390
B7 40 °C vs. B9 40 °C 1.000
B7 40 °C vs. B 40 °C 0.064
B9 40 °C vs. B 40 °C 0.012b
B 40 °C vs. A 40 °C 0.0003b
B 40 °C vs. C 40 °C 0.059
C 40 °C vs. A 40 °C 1.000

Note: the calculations for the slopes did not include data from week 0 or week 29 for the B, A, and C formulations

RT room temperature

aThe difference in slopes changes significance when week 29 for B, A, and C at the room temperature storage are included in the model fits

bThe difference in slopes is significant at the overall 0.05 significance level