Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Feb 26;7:64. doi: 10.3389/fphys.2016.00064

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016 Fourie, Ells, Swart, Sebolai, Albertyn and Pohl.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Illustration of competition between Candida albicans and Pseudomonas aeruginosa. Pseudomonas aeruginosa attaches to C. albicans hyphae and kills hyphal cells through secreted hydrolytic enzymes such as hemolytic phospholipase C (PlcH) and phenazines such as pyocyanin and 5-methylphenazine-1-carboxylic acid (5-MPCA). 3-oxo-homoserine lactone produced by P. aeruginosa and phenazines inhibit filamentation by C. albicans, similar to farnesol, produced by C. albicans. Pseudomonas aeruginosa lipopolysaccharide (LPS) inhibits C. albicans filamentation. Ethanol production is increased by the fungus, inhibiting the motility of P. aeruginosa (adapted from Lindsay and Hogan, 2014).