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. 2016 Feb 25;11(2):e0150145. doi: 10.1371/journal.pone.0150145

Table 3. Comparison of VCS progressors and non-progressors.

Parameter Progressors (n = 34) Non-progressors (n = 115) P
Age (years) 63.15 ± 12.11 57.24 ± 12.9 0.019
Gender (male %) 61.8 51.3 0.283
Diabetes (%) 47.1 44.3 0.780
Cardiovascular
    BMI (kg/m2) 22.19±2.41 22.85±3.64 0.224
    Previous CVD (%) 38.2 32.2 0.511
    Smoking habit (%) 41.2 40.9 0.974
    Antihypertensive drugs (%)
        RAS blockers 55.9 55.7 0.981
        Beta-blockers 44.1 53 0.360
        CCB 58.8 45.2 0.163
Anti-platelet agents (%)
    Statins (%) 35.3 29.6 0.525
    Ca-based P binder (%) 67.6 84.3 0.031
    Vitamin D analogue (%) 26.5 27 0.955
HD
    Dialysis duration (months) * 76 (64–108) 76 (61–121) 0.475
    spKt/V 1.58 ± 0.20 1.59 ± 0.20 0.670
RAGE
    Log S100A12 (ng/mL) 6.02 ± 0.85 5.63 ± 0.83 0.016
    Log sRAGE (pg/mL) 7.54 ± 0.54 7.60 ± 0.67 0.612
    Log IL-6 (pg/mL) 0.49 ± 0.69 0.65 ± 0.71 0.238
Laboratory (Time-averaged)
    HDL-C (mg/dL) 40.5 ± 10.92 41.62 ± 11.85 0.624
    LDL-C (mg/dL) 67.22 ± 16.53 64.36 ± 17.75 0.404
    Albumin (g/L) 3.86 ± 0.33 3.88 ± 0.32 0.849
    Hemoglobin (g/dL) 10.88 ± 0.73 10.93 ± 0.7 0.763
    Ca (mg/dL) 8.77 ± 0.46 8.75 ± 0.49 0.879
    P (mg/dL) 4.62 ± 0.78 4.57 ± 0.91 0.800
    iPTH (pg/mL) 239.95 ± 244.33 270.71 ± 227.59 0.497
    hsCRP (mg/dL) 1.3 ± 1.5 1.18 ± 1.26 0.643
    25D (ng/mL) 11.66 ± 4.67 10.88 ± 3.37 0.280
    1,25D (pg/mL) 18.01 ± 4.04 17.31 ± 3.96 0.369

Abbreviations: BMI, body mass index; CVD, cardiovascular disease; MAP, mean artery pressure; RAS, renin-angiotensin system; CCB, calcium channel blocker; Ca, calcium; spKt/V, single pool Kt/V;; sRAGE, soluble receptor for advanced glycation end product; IL-6, interleukin 6; HDL-C, HDL cholesterol; LDL-C, LDL cholesterol; TG, triglyceride; Ca, calcium; P, phosphorus;; iPTH, intact parathyroid hormone; hsCRP, highly sensitive C-reactive protein; 25D, 25-hydroxyvitamin D; 1,25D, 1,25-dihydroxyvitamin D

* Median, interquartile range