Table 4. Odds ratios for associations between S100A12 or sRAGE and vascular calcification progression using stepwise logistic regression models.

	Log S100A12 (ng/mL)		Log sRAGE (pg/mL)
	OR (95% CI)	P	OR (95% CI)	P
Crude	1.828 (1.108–3.018)	0.018	0.856 (0.473–1.551)	0.609
Model 1	1.942 (1.154–3.270)	0.012	0.838 (0.447–1.571)	0.582
Model 2	2.021 (1.193–3.412)	0.009	0.819 (0.427–1.569)	0.546
Model 3	2.280 (1.277–4.070)	0.005	0.756 (0.373–1.532)	0.437
Model 4	2.622 (1.371–5.016)	0.004	0.644 (0.302–1.374)	0.255

Model 1: adjusted for age, sex, and BMI; Model 2: model 1 + adjustment for cardiovascular disease and risk factors (previous CVD, diabetes mellitus, smoking habit, and dialysis duration); Model 3: model 2 + adjustment for laboratory parameters (time-averaged HDL-C, time-averaged LDL-C, time-averaged Ca, time-averaged P, time-averaged iPTH, time-averaged hsCRP, time-averaged 25D, time-averaged 1,25D, time-averaged spKt/V, and log IL-6); Model 4: model 3 + adjustment for medication (RAS blockers, beta-blockers, CCB, statin and Ca-based P binders). OR (95% CI) denotes odds ratio (95% confidence interval).