Table 4. Comparison of differences among various clinical factors between the 10 and 40 mg groups.

Factor	Difference in 10 mg group	Difference in 40 mg group	P valuea
CPK, U/L	24.6±146.2	-9.1±48.3	0.359
AST, IU/L	1.4±5.2	0.3±10.0	0.622
ALT, IU/L	0.9±8.2	0.4±19.4	0.901
Insulin, µIU/mL	-2.8±11.4	-7.3±41.2	0.599
C-peptide, pmol/mL	-0.2±0.5	-0.2±0.9	0.818
HbA1c, %	-0.3±1.1	-0.1±1.1	0.524
Glucose, mg/dL	-4.7±90.4	-23.9±61.4	0.393
TC, mg/dL	-60.9±21.6	-78.7±26.3	0.012
LDL-C, mg/dL	-55.9±20.8	-71.5±24.7	0.019
HDL-C, mg/dL	-1.4±7.9	0.7±7.5	0.351
TG, mg/dL	-47.6±76.4	-54.4±107.8	0.794
GDF-15, pg/mL	-9.5±398.7	69.7±480.0	0.527
HOMA-IR	-0.9±6.0	-1.5±6.7	0.738
hsCRP, mg/dL	-1.3±2.5	-1.3±2.4	0.979

Values are presented as mean±standard deviation.

CPK, creatine phosphokinase; AST, aspartate transaminase; ALT, alanine transaminase; HbA1c, glycosylated hemoglobin; TC, total cholesterol; LDL-C, low density lipoprotein cholesterol; HDL-C, high density lipoprotein cholesterol; TG, triglyceride; GDF-15, growth differentiation factor 15; HOMA-IR, homeostasis model assessment-estimated insulin resistance; hsCRP, high-sensitivity C-reactive protein.

^aP value determined using the Mann-Whitney U test.