Table 5. Pearson's correlation coefficient between the differences in GDF-15 levels and the differences in various variables.
| Variable | Difference in GDF-15 | P value |
|---|---|---|
| CPK (difference), U/L | -0.006 | 0.971 |
| AST (difference), IU/L | -0.090 | 0.536 |
| ALT (difference), IU/L | -0.074 | 0.608 |
| Insulin (difference), µIU/mL | 0.196 | 0.314 |
| C-peptide (difference), pmol/mL | 0.232 | 0.109 |
| HbA1c (difference), % | 0.196 | 0.173 |
| Glucose (difference), mg/dL | 0.053 | 0.716 |
| TC (difference), mg/dL | -0.062 | 0.671 |
| LDL-C (difference), mg/dL | -0.036 | 0.806 |
| HDL-C (difference), mg/dL | -0.124 | 0.396 |
| TG (difference), mg/dL | -0.042 | 0.773 |
| HOMA-IR (difference) | 0.097 | 0.505 |
| hsCRP (difference), mg/dL | 0.016 | 0.504 |
All clinical factors are differences of the mean. Difference: after medication–before medication.
GDF-15, growth differentiation factor 15; CPK, creatine phosphokinase; AST, aspartate transaminase; ALT, alanine transaminase; HbA1c, glycosylated hemoglobin; TC, total cholesterol; LDL-C, low density lipoprotein cholesterol; HDL-C, high density lipoprotein cholesterol; TG, triglyceride; HOMA-IR, homeostasis model assessment-estimated insulin resistance; hsCRP, high-sensitivity C-reactive protein.