Figure 4.
GRHL2 expression in the cochlea of the common marmoset (a, b) GRHL2 expression was observed in the lateral wall spiral ligament, hair cells, supporting cells, and spiral ganglion neurons. No expression was observed in the stria vascularis. (c) Supporting cell expression was broadly observed between the inner sulcus and outer sulcus cells, and GRHL2 expression was observed in the inner and outer hair cells. (d,e) In the spiral ligament, GRHL2 expression was observed in type I and III fibrocytes and co-localized with CALDESMON. The nuclei were counterstained with Hoechst (blue). Scale bar: 200 μm in a, 100 μm in (b–e). Middle turns in (a–e). SV: stria vascularis, OC: organ of Corti, SGN: spiral ganglion neurons, ISC: Inner sulcus cells, OSC: Outer sulcus cells, HC: Hensen’s cells, DC: Deiters’ cells, IPC: inner pillar cells, OHC: Outer hair cells, IHC: Inner hair cells, SLF: spiral ligament fibrocytes (I-V: Type I-V).