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. 2016 Feb 26;6:22243. doi: 10.1038/srep22243

Table 1. Information summary of 51 eligible studies included in this meta-analysis.

Author [reference] Country Year Cancer type Ethnicity No. of case/control Study type Control source DNA source Measurement methods
Gabriella M. Anic et al._melonoma11 a USA 2013 melanoma Caucasian 198/372 retrospective hospital-based leukocyte quantitative PCR
Gabriella M. Anic et al._BCC11 a USA 2013 basal cell carcinoma Caucasian 185/372 retrospective hospital-based leukocyte quantitative PCR
Gabriella M. Anic et al._SCC11 a USA 2013 squamous cell carcinoma Caucasian 136/372 retrospective hospital-based leukocyte quantitative PCR
Hongmei Nan et al.12 USA 2011 cutaneous melanoma Caucasian 557/579 retrospective population-based leukocyte quantitative PCR
Jiali Han et al._melonoma13 USA 2009 melanoma Caucasian 204/222 prospective population-based leukocyte quantitative PCR
Jiali Han et al._SCC13 USA 2009 squamous cell carcinoma Caucasian 254/273 prospective population-based leukocyte quantitative PCR
Jiali Han et al._BCC13 USA 2009 basal cell carcinoma Caucasian 282/306 prospective population-based leukocyte quantitative PCR
Geyu Liang et al._SCC14 USA 2011 squamous cell carcinoma Caucasian 241/241 retrospective population-based leukocyte quantitative PCR
Geyu Liang et al._BCC14 USA 2011 basal cell carcinoma Caucasian 623/1943 retrospective population-based leukocyte quantitative PCR
Laura S. Burke et al.15 USA 2013 melanoma Caucasian 119/208 retrospective family-based whole blood or EBV-transformed lymphocytes quantitative PCR
Xifeng Wu et al._RCC16 USA 2003 renal cell carcinoma Caucasian 32/32 retrospective population-based leukocyte Q-FISH
Xifeng Wu et al._BLC16 USA 2003 bladder cancer Caucasian 135/135 retrospective population-based leukocyte Q-FISH
Lisa Mirabello et al.17 USA 2009 prostate cancer Caucasian 612/1049 retrospective population-based leukocyte quantitative PCR
B Julin et al.18 USA 2015 prostate cancer Caucasian 922/935 retrospective population-based leukocyte quantitative PCR
Lauren M. Hurwitz et al.19 USA 2014 prostate cancer Caucasian 112/63 retrospective family-based leukocyte quantitative PCR
Jonathan N. Hofmann et al.20 USA 2013 renal cell carcinoma Caucasian 209/410 prospective population-based leukocyte quantitative PCR
Jonathan N. Hofmann et al._Caucasian21 USA 2011 renal cell carcinoma Caucasian 658/550 retrospective population-based whole blood quantitative PCR
Jonathan N. Hofmann et al._African American21 USA 2011 renal cell carcinoma African American 233/344 retrospective population-based whole blood quantitative PCR
Monica McGrath et al.22 USA 2007 bladder cancer Caucasian 184/192 retrospective population-based leukocyte quantitative PCR
Karin Broberg et al.23 Sweden 2005 bladder cancer Caucasian 63/93 retrospective population-based buccal cell quantitative PCR
Andrew J. Pellatt et al.24 USA 2012 colon rectal cancer Caucasian 525/746 retrospective population-based whole blood quantitative PCR
Yong Cui et al.25 China 2012 colorectal cancer Asian 512/549 retrospective Population-based leukocyte quantitative PCR
Qin Qin et al.26 China 2014 colorectal cancer Asian 628/1256 retrospective hospital-based leukocyte quantitative PCR
Lifang Hou et al.27 USA 2009 gastric cancer Caucasian 300/416 retrospective population-based leukocyte quantitative PCR
Rosa Ana Risques et al.28 USA 2007 esophageal adenocarcinoma Caucasian 38/300 prospective population-based leukocyte quantitative PCR
Qianqian Yu et al.29 China 2014 esophageal squamous cell carcinoma Asian 308/309 retrospective hospital-based lymphocyte quantitative PCR
Jiangbo Du et al.30 China 2015 gastric cancer Asian 1136/1102 retrospective population-based leukocyte quantitative PCR
Xiaonan Liu et al.31 China 2009 gastric cancer Asian 396/376 retrospective hospital-based leukocyte quantitative PCR
Jinliang Xing et al.32 USA 2009 esophageal cancer Caucasian 94/92 retrospective hospital-based leukocyte quantitative PCR
Maria M. Gramatges et al.33 USA 2010 breast cancer Caucasian 102/50 retrospective population-based leukocyte quantitative PCR
Andrew J. Pellatt et al.34 USA 2013 breast cancer Caucasian 728/720 retrospective population-based leukocyte quantitative PCR
Jing Shen et al.35 USA 2009 breast cancer Caucasian 1026/1070 retrospective population-based leukocyte quantitative PCR
Immaculata De Vivo et al.36 USA 2009 breast cancer Caucasian 896/917 prospective population-based leukocyte quantitative PCR
Sangmi Kim et al.37 USA 2011 breast cancer Caucasian 342/735 prospective population-based leukocyte quantitative PCR
Jing Shen et al.38 USA 2007 breast cancer Caucasian 283/347 retrospective family-based leukocyte quantitative PCR
Yun-Ling Zheng et al.39 USA 2010 breast cancer Caucasian 292/335 retrospective population-based leukocyte Q-FISH
Shimian Qu et al.40 USA 2012 breast cancer Asian 601/695 prospective population-based leukocyte quantitative PCR
Xifeng Wu et al._LC16 USA 2003 lung cancer Caucasian 54/54 retrospective population-based leukocyte Q-FISH
Min Shen et al.41 USA 2011 lung cancer Caucasian 230/229 prospective population-based leukocyte quantitative PCR
Qing Lan et al.42 USA 2013 lung cancer Asian 215/215 prospective population-based leukocyte quantitative PCR
Beatriz Sanchez-Espiridion et al._LAC43 USA 2014 lung adenocarcinoma Caucasian 706/706 retrospective hospital-based leukocyte quantitative PCR
Beatriz Sanchez-Espiridion et al._LSCC43 USA 2014 lung squamous cell carcinoma Caucasian 320/320 retrospective hospital-based leukocyte quantitative PCR
Wei Jie Seow et al.44 USA 2014 lung cancer Caucasian 847/847 prospective Population-based leukocyte quantitative PCR
Bing Sun et al.45 USA 2015 lung cancer Caucasian 191/207 retrospective Population-based hospital-based lymphocyte Q-FISH
Jin Sung Jang et al.46 Korea 2008 lung cancer Asian 243/243 retrospective hospital-based leukocyte quantitative PCR
Yang Zhang et al._OCC47 a USA 2013 oral cavity cancer Caucasian 137/335 retrospective hospital-based lymphocyte quantitative PCR
Yang Zhang et al._OPC47 a USA 2013 oropharyngeal squamous cell carcinoma Caucasian 188/335 retrospective hospital-based lymphocyte quantitative PCR
Da-Tian Bau et al.48 USA 2013 oral squamous cell carcinoma Caucasian 92/394 retrospective hospital-based leukocyte quantitative PCR
Xifeng Wu et al._HNC16 USA 2003 head and neck cancer Caucasian 92/92 retrospective population-based leukocyte Q-FISH
Qing Lan et al.49 USA 2009 non-Hodgkin lymphoma Caucasian 107/107 retrospective population-based leukocyte quantitative PCR
Fatemeh Saberi Hosnijeh et al.50 Iran 2014 B-cell lymphoma Caucasian 414/414 retrospective population-based leukocyte quantitative PCR
Thomas A. Widmann et al.51 Germany 2007 non-Hodgkin’s lymphoma Caucasian 40/40 retrospective hospital-based lymphocyte Flow-FISH
Juan Liu et al.52 China 2011 hepatitis B virus-related hepatocellular carcinoma Asian 240/240 retrospective hospital-based leukocyte quantitative PCR
Shannon M. Lynch et al.53 USA 2013 pancreatic cancer Caucasian 193/660 prospective population-based leukocyte quantitative PCR
Xiaoying Fu et al.54 USA 2012 hepatocellular carcinoma Asian 140/280 retrospective hospital-based circulating cell-free serum DNA quantitative PCR
Daniele Campa et al.55 Germany 2014 myeloma Caucasian 140/468 retrospective population-based leukocyte quantitative PCR
Kathryn L. Terry et al.56 USA 2012 ovarian cancer Caucasian 911/947 retrospective population-based leukocyte quantitative PCR
Farzana Walcott et al.57 USA 2013 glioma Caucasian 101/198 prospective population-based blood, buffy coat, or buccal cells quantitative PCR
Jennifer Prescott et al.58 USA 2010 endometrial cancer Caucasian 279/791 prospective population-based leukocyte quantitative PCR
Maren Weischer et al.59 Denmark 2013 mixed Caucasian 3142/41169 prospective Population-based leukocyte quantitative PCR
Lisa Mirabello et al.60 USA 2009 ovarian cancer Caucasian 99/100 retrospective population-based leukocyte quantitative PCR
Peter Willeit et al.61 Italy 2010 mixed Caucasian 92/695 prospective population-based leukocyte quantitative PCR

aThe controls were shared for different cancer types in the same publication.