Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Proposed topology of NS4B within the ER membrane with the relative positioning of the two-amphipathic helices AH1 and AH2, the two C-terminal helices H1 and H2, the four transmembrane domains (TMD) and the location of the nucleotide-binding domain (NBD). During maturation, it is suggested that AH2 may traverse the bilayer, leading to the translocation of AH1 to the opposite face of the membrane [13], [15], [17].
