Figure 3. Renal interstitial administration of Etanerceptin SS rats ameliorated glomerulosclerosis and renal interstitial fibrosis.

(A) Percent of glomeruli that were severely damaged (scored 4). (B) Percent of renal cortical area that was fibrotic. (C) Representative images of kidney sections. Arrows point to injured glomeruli. (D) Percent of kidney section area occupied by tubular casts. E. Urinary 24 hour excretion of albumin (Ualb) or total protein (Uprot). N = 4–8, *P < 0.05 vs. vehicle-treated rats.