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. 2016 Feb 26;6:22083. doi: 10.1038/srep22083

Figure 3. S. aureus 161:2-CFS induces expression of regulatory- and pro-inflammatory cytokines in FOXP3+ CD4 T-cells.

Figure 3

(a) The percentages of FOXP3+ cells and (b) the percentages of FOXP3− cells that express IL-10 (upper panel), IFN-γ (middle panel) or IL-17A (lower panel) after 24-hour stimulation with SEA (n = 6–10) or S. aureus 161:2-CFS (n = 16–18). (c) Representative facs-plots of cytokine-expression in CD25+FOXP3+ cells in isolated CD4+CD25high T-cell-cultures after 40-hour stimulation with S. aureus 161:2-CFS. (d) Representative facs-plots of cytokine-expression in cells with de novo expression of CD25 and FOXP3 in CD4+CD25-depleted T-cell-cultures after 40-hour stimulation with S. aureus 161:2-CFS. For scatter dot plots, the horizontal lines represent the median within each group.

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