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. 2016 Feb 26;6:22179. doi: 10.1038/srep22179

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(Panel a) No detectable expression of MT1-MMP protein in the normal epithelium (100×). (Panel 1b) MT1-MMP immunoreactivity was in the invasion front and was increased expression in tumor buds (100×). (Panels c,d) Intense cytoplasmic and membranous staining in ESCC (200× and 400×, respectively).