Table 3. EMT protein expression in relation to clinicopathological characteristics in Xinjiang Kazakh ESCC.
Clinicopathologica features | N | E-cadherin | χ2 | N-cadherin | χ2 | vimentin | χ2 |
---|---|---|---|---|---|---|---|
Negative | Negative | Negative | |||||
Positive | P | Positive | P | Positive | P | ||
Normal | 42 | 22 | 5.927 | 23 | 32.656 | 24 | 17.498 |
20 | 0.015 | 19 | 0.001 | 18 | <0.001 | ||
ESCC | 88 | 65 | 8 | 18 | |||
23 | 80 | 70 | |||||
Male | 55 | 42 | 0.475 | 4 | 0.587 | 10 | 0.466 |
13 | 0.491 | 51 | 0.444 | 45 | 0.495 | ||
Female | 33 | 23 | 4 | 8 | |||
10 | 29 | 25 | |||||
Age (y) | |||||||
<60 | 41 | 31 | 0.121 | 3 | 0.292 | 8 | 0.042 |
10 | 0.728 | 38 | 0.589 | 33 | 0.838 | ||
≥60 | 47 | 34 | 5 | 10 | |||
13 | 42 | 37 | |||||
Tumor invasion | |||||||
Superficial layer | 49 | 40 | 0.679 | 5 | 0.166 | 5 | 7.140 |
9 | 0.410 | 44 | 0.684 | 44 | 0.008 | ||
Deep layer | 39 | 29 | 3 | 13 | |||
10 | 36 | 26 | |||||
LN metastases | |||||||
Yes | 57 | 15 | 2.795 | 4 | 0.842 | 9 | 2.164 |
12 | 0.095 | 53 | 0.359 | 48 | 0.141 | ||
No | 31 | 18 | 4 | 9 | |||
11 | 27 | 22 | |||||
Tumor differentiation | |||||||
Well | 25 | 14 | 5.772 | 5 | 5.029 | 8 | 2.861 |
11 | 0.016 | 20 | 0.025 | 17 | 0.091 | ||
Moderate-poor | 63 | 51 | 3 | 10 | |||
12 | 60 | 53 | |||||
Stage | |||||||
I + II | 64 | 53 | 9.734 | 5 | 0.464 | 12 | 0.419 |
11 | 0.002 | 59 | 0.496 | 52 | 0.517 | ||
III+IV | 24 | 12 | 3 | 6 | |||
12 | 21 | 18 |
P-values ≤ 0.05 are indicated in bold.