Higher detail of morphologic changes in colonic tissue of rats. A: Control group (left) and model group (right); B: Single acupoint group (left) and two acupoints group (right); C: Three acupoints group (left) and medication group (right). In the model group, intestinal mucosa was deficient, the arrangement of gland was irregular and submucosa was edematous, hyperemic and infiltrated with inflammatory cells. After the different treatments, the gland, mucosa, etc. were improved significantly. The efficacy in the three acupoints and medication groups was superior to that of the single and two acupoints groups (hematoxylin-eosin staining, × 400 magnification).