Table 2.
HSI1 |
NAFLD-LFS2 |
|||||
OR | 95%CI | P value | OR | 95%CI | P value | |
Age | 0.993 | 0.986-0.999 | 0.034 | 1.017 | 1.010-1.024 | < 0.001 |
Male | 2.043 | 1.731-2.410 | < 0.001 | |||
Body mass index | 1.460 | 1.413-1.509 | < 0.001 | |||
Hypertension | 2.001 | 1.703-2.350 | < 0.001 | |||
Metabolic syndrome | 4.757 | 4.002-5.654 | < 0.001 | |||
Smoking | 1.327 | 1.144-1.539 | < 0.001 | 1.301 | 1.115-1.517 | 0.001 |
Alcohol | 1.022 | 0.881-1.186 | 0.772 | 0.902 | 0.773-1.051 | 0.186 |
Presence of H. pylori | 1.109 | 0.956-1.286 | 0.173 | 1.022 | 0.876-1.193 | 0.778 |
Fasting glucose | 1.024 | 1.020-1.027 | < 0.001 | |||
Insulin | 1.244 | 1.218-1.270 | < 0.001 | |||
HOMA-IR | 2.240 | 2.076-2.417 | < 0.001 | |||
Total cholesterol | 1.005 | 1.003-1.007 | < 0.001 | 1.004 | 1.001-1.006 | 0.001 |
Triglyceride | 1.009 | 1.007-1.010 | < 0.001 | |||
HDL-C | 0.932 | 0.925-0.940 | < 0.001 | |||
LDL-C | 1.008 | 1.006-1.010 | < 0.001 | 1.003 | 1.000-1.005 | 0.021 |
C-reactive protein | 1.410 | 1.163-1.710 | < 0.001 | 1.602 | 1.298-1.978 | < 0.001 |
Factors included in each scoring formula, such as sex, body mass index, diabetes, insulin, and metabolic syndrome components, were excluded from the analysis.
HSI: 8 × ALT/AST + body mass index (if diabetes mellitus, +2; if female, +2);
NAFLD-LFS: -2.89 + 1.18 × metabolic syndrome (yes = 1, no = 0) + 0.45 × type 2 diabetes (yes = 2, no = 0) + 0.15 × insulin (mU/L) + 0.04 × AST (U/L) - 0.94 × AST/ALT. NAFLD: Nonalcoholic fatty liver disease; HSI: Hepatic steatosis index; NAFLD-LFS: Nonalcoholic fatty liver disease liver fat score; HOMA-IR: Homeostatic model assessment of insulin resistance; HDL-C: High-density lipoprotein cholesterol; LDL-C: Low-density lipoprotein cholesterol.