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. 2016 Feb 28;22(8):2592–2600. doi: 10.3748/wjg.v22.i8.2592

Table 2.

Univariable analysis of nonalcoholic fatty liver disease according to hepatic steatosis index and nonalcoholic fatty liver disease liver fat score scores

HSI1
NAFLD-LFS2
OR 95%CI P value OR 95%CI P value
Age 0.993 0.986-0.999 0.034 1.017 1.010-1.024 < 0.001
Male 2.043 1.731-2.410 < 0.001
Body mass index 1.460 1.413-1.509 < 0.001
Hypertension 2.001 1.703-2.350 < 0.001
Metabolic syndrome 4.757 4.002-5.654 < 0.001
Smoking 1.327 1.144-1.539 < 0.001 1.301 1.115-1.517 0.001
Alcohol 1.022 0.881-1.186 0.772 0.902 0.773-1.051 0.186
Presence of H. pylori 1.109 0.956-1.286 0.173 1.022 0.876-1.193 0.778
Fasting glucose 1.024 1.020-1.027 < 0.001
Insulin 1.244 1.218-1.270 < 0.001
HOMA-IR 2.240 2.076-2.417 < 0.001
Total cholesterol 1.005 1.003-1.007 < 0.001 1.004 1.001-1.006 0.001
Triglyceride 1.009 1.007-1.010 < 0.001
HDL-C 0.932 0.925-0.940 < 0.001
LDL-C 1.008 1.006-1.010 < 0.001 1.003 1.000-1.005 0.021
C-reactive protein 1.410 1.163-1.710 < 0.001 1.602 1.298-1.978 < 0.001

Factors included in each scoring formula, such as sex, body mass index, diabetes, insulin, and metabolic syndrome components, were excluded from the analysis.

1

HSI: 8 × ALT/AST + body mass index (if diabetes mellitus, +2; if female, +2);

2

NAFLD-LFS: -2.89 + 1.18 × metabolic syndrome (yes = 1, no = 0) + 0.45 × type 2 diabetes (yes = 2, no = 0) + 0.15 × insulin (mU/L) + 0.04 × AST (U/L) - 0.94 × AST/ALT. NAFLD: Nonalcoholic fatty liver disease; HSI: Hepatic steatosis index; NAFLD-LFS: Nonalcoholic fatty liver disease liver fat score; HOMA-IR: Homeostatic model assessment of insulin resistance; HDL-C: High-density lipoprotein cholesterol; LDL-C: Low-density lipoprotein cholesterol.