Figure 7. Enhancement of mixed chimerism does not occur in the absence of transient immunosuppression or if liposomal clodronate is given intranasally.

Peripheral blood mixed chimerism, defined by the percentage of BALB/c MHC-class I (H-2K^d)-positive cells, was determined at 30 days post-BM transplantation in recipient C57BL/6 mice under the conditions specified below each plot. Mice did not receive skin transplantation. Data are representative of two independent experiments with the same pattern (total n = 6 in each group).