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. 2015 Mar 18;25(11):4430–4449. doi: 10.1093/cercor/bhv045

Figure 4.

Figure 4.

Distribution of strongly COUP-TFII-positive interneurons and colocalization patterns with calretinin, reelin, and CCK displayed in 10 radial bins from the pia to the bottom of layer III. Pyramidal cells positive for CCK were excluded. (A) Average (±SD) proportions of COUP-TFII-positive cells per bin. (B) Depth profile of the colocalization distribution of the 4 molecules shown as average of the 3 patients. Most COUP-TFII-positive cells were positive for at least one of the 3 molecules. All reelin-positive cells were COUP-TFII-positive and mostly located in layers I and upper II. Few calretinin-positive cells were COUP-TFII-negative. (C) Distribution of cells (mean ± SD) showing different colocalization patterns summed from all supragranular layers. Most COUP-TFII-positive cells are immunopositive for calretinin, and/or CCK, and/or reelin, and those immunonegative for all 3 molecules represent on average only 2.9% of cells. Note the small variation between the 3 individuals. Colour-coding of diagrams in (B) and (C) is identical.