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Receptor tyrosine kinase‐like orphan receptor 1 (ROR1) inhibits apoptosis signal‐regulating kinase 1 (ASK1) kinase activity. Results of in vitro ASK1 kinase assays with use of myc‐tagged ASK1 immunoprecipitated from ASK1‐transfected 293T cells, as well as recombinant GST‐ROR1 and maltose‐binding protein–MAPKK 6 (MBP‐MKK6) proteins purified from Escherichia coli.
