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. 2016 Feb 12;13(2):119–126. doi: 10.1177/1479164115616901

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© The Author(s) 2015

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 1. — Effect of empagliflozin treatment on markers of visceral adiposity and estimated total body fat compared with placebo. Changes from baseline to week 12 (cohort 1) and week 24 (cohort 2) are shown for (a) waist circumference, (b) estimated total body fat, (c) index of central obesity and (d) visceral adiposity index. Greater reductions were seen in adiposity measures and indices in the empagliflozin treated groups compared with placebo in both study cohorts. The p-values for adjusted means based on ANCOVA with LOCF imputation.

ANCOVA: analysis of covariance; FAS: full-analysis set; LOCF: last observation carried forward.