Table 5. Association of IL-1α rs3783553 genotypes with tumor HPV16 status in 552 SCCOP patients.
Genotypes | HPV16-positive SCCOP cases (N = 439) | HPV16-negative SCCOP cases (N = 113) | P | Adj.OR (95% CI)* | ||
---|---|---|---|---|---|---|
| ||||||
No. | % | No. | % | |||
IL-1α rs3783553 | ||||||
Ins/Del + Ins/Insa | 245 | 55.8 | 90 | 79.6 | < 0.0001 | 1.0 |
Del/Del | 194 | 44.2 | 23 | 20.4 | 3.2 (1.9-5.7) |
P value for χ2 test for genotype distribution.
Adjusted for age, sex, ethnicity, smoking and alcohol status in a logistic regression model.
Ref. = reference group.