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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Biol Blood Marrow Transplant. 2015 Jul 31;21(11):1985–1993. doi: 10.1016/j.bbmt.2015.07.029

Table 3.

Comparison of early and late causes of treatment failure after URDT and DCBT.

Events 8/8 URDT
(28/ 66, 42%)
7/8 URDT
(26/ 45, 58%)
DCBT
(17/ 55, 31%)

Before Day 180

TRM 5 (8%) 5 (11%) 12 (22%)
  Graft Failure - - 2
  GVHD - 1 4
  Organ Failure 1 - 4
  Infection 4 3 2
  Other* - 1 -

Relapse 1 (2%) 3 (7%) 1 (2%)

After Day 180

TRM 9 (14%) 12 (27%) 1 (2%)
  Graft Failure - 1 -
  GVHD 4 8 1
  Organ Failure 1 - -
  Infection 2 3 -
  Other* 2 - -

Relapse 13 (20%) 6 (13%) 3 (5%)

URDT indicates unrelated donor transplantation; DCBT, double-unit cord blood transplantation; TRM, transplant-related mortality; GVHD, graft-versus-host disease.

*

Other included one patient who died prior to day 180 of leukoencephalopathy of unknown etiology, one with recurrent breast cancer and one who died of secondary malignancy after day 180.