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. Author manuscript; available in PMC: 2016 Jul 7.
Published in final edited form as: Structure. 2015 Jun 4;23(7):1305–1316. doi: 10.1016/j.str.2015.04.017

FIGURE 1. Crystal structure of h2NLS bound to ΔIBB-Kap60.

FIGURE 1

(A) Aminoacid sequence of Heh2 and Heh1 peptides co-crystallized with ΔIBB-Kap60. In black and gray are residues visible and invisible in the crystal structures, respectively; bolded are basic residues occupying minor (left) and major (right) NLS-binding boxes; underlined are residues at position P2’ and P2. (B) Crystal structure of ΔIBB-Kap60 (gray surface) in complex with h2NLS (red ribbon). (C) Schematic diagram of the interactions between h2NLS (in red) and Kap60 residues (in gray) in a distance range of 2.5-4.5 Å. See also Figure S1.