Table 1.
Antibacterial activity of ABgp46 against several Gram-negative bacterial pathogens.
| Bacterial species | ABgp46/water | Origin/characteristics |
|---|---|---|
| P. aeruginosa PAOI | 0.03 ± 0.02 | Reference strain (ATCC 15692) |
| S. typhimurium LT2 | 0.14 ± 0.05 | Clinical strain |
| E. coli 0157:H7 | 0.17 ± 0.12 | Reference strain (CECT 4782) |
| C. sakazakii | 0.23 ± 0.26 | Reference strain (CECT 858) |
| K. oxytoca | 0.18 ± 0.13 | Reference strain (ATCC 13182) |
| A. baumannii #1∗ | 1.79 ± 0.38 | Clinical strain (TI, AMC, TZP, CE, AZ, ME, AN, GM, NN, CP, PF, TS) |
| A. baumannii #2∗ | 0.93 ± 0.25 | Clinical strain (TI, AMC, TZP, CE, AZ, ME, AN, GM, NN, CP, PF, TS) |
| A. baumannii #3∗ | 1.00 ± 0.32 | Clinical strain (TI, AMC, TZP, CE, CEF, AZ, ME, GM, NN, CP, PF, TS) |
| A. baumannii #4∗ | 0.81 ± 0.21 | Clinical strain (TI, AMC, TZP, CE, CEF, AZ, ME, GM, NN, CP, PF, TS) |
| A. baumannii #5∗ | 0.37 ± 0.19 | Clinical strain (TI, AMC, TZP, CE, CEF, AZ, ME, CP, PF) |
| A. baumannii #6∗ | 1.20 ± 0.46 | Clinical strain (TI, AMC, TZP, CE, CEF, AZ, ME, CP, PF) |
Averages ± standard deviations for all experiments are given for n = 4 repeats. Marked in bold are ≥1 log reduction units observed. ∗Known patterns of antibiotic resistance provided by the Hospital of Braga, based on susceptibility tests performed according to the NCCLS for antibiotic resistance; TI, Ticarcillin; AMC, amoxicillin/clavulanic acid; TZP, piperacillin/tazobactam; CE, ceftazidime CEF, Cefepime; AZ, Aztreonam, ME, meropenem; AN, amikacin; GM, gentamicin; NN, tobramycin; CP, ciprofloxacin; PF, Pefloxacin; TS, Trimethoprim/Sulfametoxazol.