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. Author manuscript; available in PMC: 2016 Feb 26.
Published in final edited form as: Compr Physiol. 2014 Oct;4(4):1605–1637. doi: 10.1002/cphy.c130005

Figure 11.

Figure 11

Localization of NDCBE to the hippocampus of the human brain (adapted, with permission, from 81). (B) Effects of knockout of NDCBE (Slc4a8) on Na+-dependent pHi changes in intercalated cells in mice cortical collecting ducts (adapted, with permission, from 187). Traces are the average of pHi changes recorded when luminal Na+ was removed and readded, in the presence of extracellular HCO3−. The data provides functional evidence for the presence of NDCBE in the apical membrane, which is important for reabsorption of Na+ by these cells.