Skip to main content
. Author manuscript; available in PMC: 2016 Feb 26.
Published in final edited form as: Compr Physiol. 2014 Oct;4(4):1605–1637. doi: 10.1002/cphy.c130005

Figure 3.

Figure 3

Schematic diagram showing the rationale for determination of whether HCO3− or CO3 2− is the transported ion. It has been suggested (38, 292) that it is possible to distinguish between HCO3− and CO3 2− transport by measuring pH in the extracellular space near the membrane following a sudden change in transport activity, before and after inhibition of the carbonic anhydrase. If CO3− is the transported species an exaggerated decrease in pH would develop when the carbonic anhydrase is inhibited, while if HCO3− is the transported species a blunted decrease in pH would be the result. From (38).