. Author manuscript; available in PMC: 2016 Feb 26.

Published in final edited form as: Compr Physiol. 2014 Oct;4(4):1605–1637. doi: 10.1002/cphy.c130005

Table 3.

Amino Acid Residues in NBCe1 Identified as Sites for Ion Transport

Domain	Residue	Potential role	Reference
Nt	Arg²⁹⁸, Glu⁹¹	HCO₃⁻ permeation tunnel	(58)
TM1	Ser⁴²⁷	Na⁺ binding or voltage sensor	(91)
TM1	Ala⁴²⁸, Ala⁴³⁵, Thr⁴⁴²	Ion translocation in the pore	(364)
TM5	Asp⁵⁵⁵	Anion selectivity	(350)
	Lys⁵⁵⁸	Pore entry or DIDS-binding site	(346)
	Lys⁵⁵⁹	DIDS-binding site	(203)
EL4	not specified	Electrogenicity	(62)
TM6	not specified	Functional unit	(63)
TM8	L⁷⁵⁰	Ion translocation in the pore	(210)
TM12	not specified	Functional unit	(63)