Table 3.
Domain | Residue | Potential role | Reference |
---|---|---|---|
Nt | Arg298, Glu91 | HCO3− permeation tunnel | (58) |
TM1 | Ser427 | Na+ binding or voltage sensor | (91) |
Ala428, Ala435, Thr442 | Ion translocation in the pore | (364) | |
TM5 | Asp555 | Anion selectivity | (350) |
Lys558 | Pore entry or DIDS-binding site | (346) | |
Lys559 | DIDS-binding site | (203) | |
EL4 | not specified | Electrogenicity | (62) |
TM6 | not specified | Functional unit | (63) |
TM8 | L750 | Ion translocation in the pore | (210) |
TM12 | not specified | Functional unit | (63) |