Figure 4.

The levels of mRNA and protein of TGF-β1 and CTGF in the lungs. (A) Relative expression of TGF-β1 and CTGF mRNA. (B) Expression of TGF-β1 and CTGF protein in the lungs. Blank control group, non-sensitized and nontreated; model group, sensitized and vehicle-treated; DEX group, sensitized and DEX-treated; SIN groups, sensitized and SIN-treated (25, 50 and 75 mg/kg). All results are presented as the mean ± standard deviation. ^##P<0.01 vs. the control group; ^**P<0.01 or ^*P<0.05 vs. the model group; ^ΔΔP<0.01 or ^ΔP<0.05 vs. the DEX group. TGF-β1, transforming growth factor-β1; CTGF, connective tissue growth factor; DEX, dexamethasone; SIN, sinomenine.