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Sinomenine treatment reduced TGF-β1 expression in lung tissue from ovalbumin-challenged mice. Positive staining is depicted in brown and the nuclei are stained blue. Positive staining highlighted TGF-β1 expression in the epithelium, macrophages, leukocytes and smooth muscle. (A) Control group; (B) model group; (C) dexamethasone group; (D) 25 mg/kg sinomenine group; (E) 50 mg/kg sinomenine group; (F) 75 mg/kg sinomenine group. TGF-β1, transforming growth factor-β1.
