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Effect of Trx1 on cell viability and cell damage following exposure to OGD/R. (A) Cell viability was measured using the MTS assay. (B) Cell damage was evaluated with LDH levels. Values are expressed as the mean ± standard error of the mean (n=6 from 3 independent experiments). *P<0.05, **P<0.01 vs. the control; #P<0.05, ##P<0.01 vs. the si-Trx1 group. Trx1, thioredoxin 1; LDH, lactate dehydrogenase; si, small interfering; OGD/R, oxygen glucose deprivation/reperfusion.
