Figure 1.
EBD concentration in BALF following CPB. Animals were sacrificed at different time points prior to or following CPB surgery (Pre-CPB, 0 h after CPB, 12 h after CPB, 24 h after CPB and 48 h after CPB). In the CPB + PP2 group, 1 mg/kg PP2 was intraperitoneally injected 30 min prior to CPB. &P<0.05, compared with the sham group; #P<0.05, compared with the CPB + PP2 group. EBD, Evans Blue Dye; BALF, bronchoalveolar lavage fluid; CPB, cardiopulmonary bypass; PP2, 4-amino-5-(4-chlorophenyl)-7-(di methylethyl)pyrazolo[3,4-d]pyrimidine.