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. 2016 Feb 4;13(3):2476–2484. doi: 10.3892/mmr.2016.4868

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Copyright: © Li et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Effects of oxaliplatin and PT-100 combination therapy on the number of pro-tumorigenic immune cells in CT26 colon cancer cell-derived murine xenograft tumors. (A–C) Analysis of CD11b+ CD11c+ tumor-associated dendritic cells. (D and E) Analysis of CD11b+ F4/80+ tumor-associated macrophages. Cells were gated according to the isotype control. Upper circle: M2 macrophage, CD11b⁺ and F4/80⁺; lower circle: M1 macrophage, CD11b⁺ and F4/80⁻. ^*P<0.05 vs. the saline vehicle control. Values are expressed as the mean ± standard error of the mean. imDC, immature dendritic cells; TIDC, tumor-infiltrating dendritic cells.