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Expression of apoptosis-associated proteins, as determined by western blotting. Fas and B-cell lymphoma 2 (Bcl-2)-associated X protein (Bax) expression levels were markedly increased under serum deprivation conditions with or without recombinant (r)CCN3 treatment, whereas Bcl-2 expression was decreased. A markedly different trend in Bax and Bcl-2 expression was detected following treatment with rCCN3. FBS, fetal bovine serum.
