Table 4. Effects of salt on MICs of Hst 5, P113, di-18Hc and hybrid peptides against Candida strains.
MICs (μg/ml) | ||||||
---|---|---|---|---|---|---|
NaCl Conc (mM) | C. albicans SC5413 | C. albicans CCARM14020 | C. albicans CCARM 14021 | C. albicans CCARM 14022 | C. guilliermondi CCARM 14018 | C. guilliermondi CCARM 14019 |
Hst 5 | ||||||
0 | 8–16 | 8–16 | 4–8 | 8–16 | 1–2 | 2–4 |
150 | 32< | 32< | 32< | 32< | 32< | 32< |
P113 | ||||||
0 | 4–8 | 4–8 | 4–8 | 8–16 | 0.5–1 | 0.5–1 |
150 | 32< | 32< | 32< | 32< | 32< | 32< |
HHP1 | ||||||
0 | 2–4 | 2–4 | 2–4 | 4–8 | 1–2 | 1–2 |
150 | 32< | 32< | 32< | 32< | 32< | 8–16 |
di-PH2 | ||||||
0 | 1–2 | 1–2 | 1–2 | 2–4 | 0.5–1 | 0.5–1 |
150 | 32< | 32< | 32< | 32< | 32< | 1–2 |
di-WP2 | ||||||
0 | 2–4 | 4–8 | 4–8 | 4–8 | 2–4 | 4–8 |
150 | 8–16 | 16–32 | 8–16 | 16–32 | 2–4 | 4–8 |
di-18Hc | ||||||
0 | 2–4 | 2–4 | 2–4 | 2–4 | 2–4 | 4–8 |
150 | 16–32 | 16–32 | 16–32 | 16–32 | 4–8 | 4–8 |