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. 2016 Feb 26;11(2):e0149621. doi: 10.1371/journal.pone.0149621

Fig 3. The relative distribution of LWAS association types.

Fig 3

Distribution of the top 105 highest-ranking implicit gene-disease pairs determined by manual inspection: Type I Gene family member (n = 71) represents gene-disease associations where a family member of the gene is causing the disease or a disease with very large phenotypic overlap; Type II Negation (n = 4) and Type III Homonym (n = 11) represent different classes of LWAS false positives composing 14% of the cases. Type IV Novel association (n = 19) indicates gene-disease associations of promise for follow up investigations.